EPISODE 39 - Cognitive Decline, Alzheimer’s Disease & Potential Benefits of Low-Carb & Ketogenic Diets w/ Amy Berger

In this episode, Dr. Bubbs interviews nutrition expert and author of the Alzheimer’s Antidote, Amy Berger MS, who takes a deep dive into topics of brain health, cognitive decline and Alzheimer’s disease. Amy discusses how Alzheimer’s disease is an energy crisis in the brain, how the brain cells are effectively “starving” for fuel and the potential role low-carb and ketogenic diets may play in providing the brain with an alternate and effective fuel source. She also unpacks the physiology of beta-amyloid plaques, neurofibrillary tangles, and the critical role of cholesterol and key nutrients like choline and vitamin B12 in brain health. Lots of actionable and insightful tips here from Amy!

"Lay-Ups" In This Episode

1)          In Alzheimer’s disease is an energy crisis in the brain

2)          Brain cells, called neurons, are struggling to metabolize glucose effectively and “starving” for fuel.

3)          Alzheimer’s disease has been dubbed “type-3 diabetes” in the medical literature.

"Performance Hacks" From This Episode

1)          The predominant abnormality in Alzheimer’s disease (AD)is a reduction in the rate of glucose uptake by the brain (i.e. CMRglu) and AD patients have shown up to 45% reductions in CMRglu.

2)          Beta-amyloid plaques are present in higher amounts in AD patients, formed for a protective reason, however when produced in excess (often due to chronically high insulin levels) contribute to cognitive decline.

3)          The brain contains 25% of the body’s total cholesterol amount and higher cholesterol levels are associated with less likelihood of cognitive decline in old age.

Coffee Talk

Amy’s morning Coffee + cream + stevia

About Amy Berger

Amy Berger, MS, CNS, NTP, is a Certified Nutrition Specialist and Nutritional Therapy Practitioner. She is a US Air Force veteran who now specializes in using low-carbohydrate nutrition to help people reclaim their vitality through eating delicious, wholesome foods, and teaching them that achieving vibrant health doesn’t require starvation, deprivation, or living at the gym. Her motto is, “Real people need real food!” You can read her blog at http://www.tuitnutrition.com/, where she writes about a wide range of health and nutrition-related topics, such as insulin, metabolism, weight loss, thyroid function, and more. Follow Amy on Twitter too @tuitnutrition

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EPISODE 15 - The Obesity-Diabetes Epidemic and The Impacts of Fasting w/ Dr. Jason Fung MD

In this episode, Dr. Bubbs interviews obesity and diabetes expert Dr. Jason Fung MD, exploring the high blood sugar and insulin epidemic that affects all Western countries today. Dr. Fung discusses the flaws in the "calories in vs calories out" model for weight loss, the importance of the liver in controlling healthy blood sugars, how chronically high insulin levels impact long-term weight gain and how constant snacking creates the ideal environment for weight gain and hyperinsulinemia. Dr. Jason also highlights some simple, easy and actionable take-aways for clients looking to lose weight, improve blood sugar levels and overall health. 

Obesity & Diabetes (Type-2) "Lay-Ups" From This Episode

1) Weight gain is a hallmark of type-2 diabetes and chronically high insulin levels.

2) Type-2 diabetes is a disease of too much insulin. It's NOT an incurable, progressive disease.

3) Conventional medical practice is to treat the symptoms of diabetes (high blood sugars) and not the root cause (the underlying high insulin).

Hyperinsulinemia "Performance Hacks" In This Episode

1) During "fasting" your body changes fuel source and preferentially burns body-fat for fuel.

2) Fasting dramatically increases growth hormone levels to preserve lean muscle during "non-eating" periods.

3) WeFa.st - Silicon-valley group achieving improved mental clarity and creativity at work through fasting. 

Coffee Talk

Dr. Fung's "Simple and Efficient" Black Coffee with intermittent fasting 

About Dr. Jason Fung

Dr. Jason Fung earned his medical degree at the University of Toronto, where he also completed his internal medicine residency before heading to the University of California, Los Angeles, for his fellowship in nephrology. He currently practices as a kidney specialist in Toronto. He is the chief of the department of medicine at Scarborough General Hospital. In addition to clinical medicine, he is also on the board of directors of Low Carb Diabetes Association and the scientific editor of the Journal of Insulin Resistance.

During the course of treating thousands of patients, it became clear to Dr. Fung that the epidemic of type 2 diabetes and obesity was getting worse. The prevailing dietary recommendations to reduce dietary fat and calories were clearly ineffective. Thus, He founded the Intensive Dietary Management Program to provide a unique treatment focus for type 2 diabetes and obesity: rather than focusing on medications, this clinic focuses on dietary changes that are simple yet effective.

In March 2016, Greystone Books published Dr. Fung’s first book, The Obesity Code, which explores the underlying hormonal imbalance that leads to obesity and recommends effective strategies that address the root causes of weight gain. His second book ‘The Complete Guide to Fasting’ was published in October 2016. This offers a practical guide to all matters related to fasting, including fasting regimens, what to expect, how to deal with problems, and simple remedies.

The Accord Study - http://www.nejm.org/doi/full/10.1056/NEJMoa0802743#t=article

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